DERL1 Polyclonal Antibody, 50ul Protein Analysis The classification of glutamate receptors

The classification of glutamate receptors is based on their activation by different pharmacologic agonists

The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development

one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain

The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events

Diseases associated with AGR3 include breast abscess and ritter's disease

DERL1 Polyclonal Antibody, 50ul Protein Analysis The classification of glutamate receptorsThe protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance