M-RIP Polyclonal Antibody, 100ul[BT-AP05559] Supplements The type I hair keratins

The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription

Read-through transcription has been observed between this locus and the upstream PIR (GeneID: 8544) locus

This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain

with no expression found in 80% of tumor cell lines

This gene was identified based on sequence similarity to a highly conserved Saccharomyces cerevisiae gene encoding a pre-ribosomal protein

M-RIP Polyclonal Antibody, 100ul[BT-AP05559] Supplements The type I hair keratinsMPRIP (Myosin Phosphatase Rho Interacting Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include actin binding. Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as