Rb Polyclonal Antibody, 50ul[BT-AP07693] Cell Transfection which are auxiliary proteins associating

which are auxiliary proteins associating with functional Kv-alpha subunits

Mutations in this gene cause hereditary hemorrhagic telangiectasia| also known as Osler-Rendu-Weber syndrome 1| an autosomal dominant multisystemic vascular dysplasia

Functional studies in mice determined that this protein plays a role in vestibular morphogenesis

This protein is differentially phosphorylated and is expressed in a wide variety of human tissues

and endothelial cells

Rb Polyclonal Antibody, 50ul[BT-AP07693] Cell Transfection which are auxiliary proteins associatingThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.