Gamma Tubulin mouse Monoclonal Antibody(6C12), 20ul Bio-Reaction Tube Mutations in OCRL cause oculocerebrorenal

Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease

Three transcript variants encoding the same protein have been found for this gene

granule enzyme release

a cell death regulator

The encoded protein binds to single-stranded DNA coated with replication protein A

Gamma Tubulin mouse Monoclonal Antibody(6C12), 20ul Bio-Reaction Tube Mutations in OCRL cause oculocerebrorenalThis gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.