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TRAP220 Polyclonal Antibody, 100ul[BT-AP09180] Deep Well Plates Repressor that binds to DNA

SKU: 87868835527

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TRAP220 Polyclonal Antibody, 100ul[BT-AP09180] Deep Well Plates Repressor that binds to DNAThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED1 (mediator complex subunit 1) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.

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Description

Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides

The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds

Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3

and its gene mutation and increased expression may be associated with human cancer

TRAP220 Polyclonal Antibody, 100ul[BT-AP09180] Deep Well Plates Repressor that binds to DNAThe activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED1 (mediator complex subunit 1) is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.

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