Dynein IC2 Polyclonal Antibody, 50ul Bio-Reaction Tube Allelic variations in this gene

Allelic variations in this gene are associated with heparin cofactor II deficiency

It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus

subcellular location:Localized in discrete vesicular and perinuclear structure

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus

It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4

Dynein IC2 Polyclonal Antibody, 50ul Bio-Reaction Tube Allelic variations in this geneThe protein encoded by DNAI2 (dynein axonemal intermediate chain 2) belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in DNAI2 are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for DNAI2.