PI4KA Rabbit Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Phosphatidylinositol breakdown products are ubiquitous

Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth

|Contains 1 PA (protease associated) domain

Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified

Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats

has also been studied because of its expression in human tumors

PI4KA Rabbit Polyclonal Antibody, 50ul ROS/Nitric Oxide Detection Phosphatidylinositol breakdown products are ubiquitousThis gene encodes a phosphatidylinositol (PI) 4 kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4 5 bisphosphate. The mammalian PI 4 kinases have been classified into two types II and III based on their molecular mass and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine.