Histone H2A Polyclonal Antibody, 100ul[BT-AP03999] Nucleic Acid Isolation & Purification A second transcript variant has

A second transcript variant has been described| but its full length nature has not been determined

may interact with and regulate effector molecules (Gilman

are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings

Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes

The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex

Histone H2A Polyclonal Antibody, 100ul[BT-AP03999] Nucleic Acid Isolation & Purification A second transcript variant hasHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.