PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome resides in the critical region

resides in the critical region for VCFS/DGS on 22q11

The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity

Our adenoviral packaging system can accommodate large gene fragments and ensures high-level expression of target genes

This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation

PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome resides in the critical regionPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.