FoxO3A Polyclonal Antibody, 50ul[BT-AP03334] ROS/Nitric Oxide Detection Defects in this gene are

Defects in this gene are a cause of Peters-plus syndrome (PPS)

It also interacts with multiple proteins including calmodulin| CABP1| enkurin| Na(+)-H+ exchange regulatory factor (NHERF )| interferon-induced GTP-binding protein (MX1)| ring finger protein 24 (RNF24)| and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)

Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene

This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues

LAMA2 encodes the alpha 2 chain

FoxO3A Polyclonal Antibody, 50ul[BT-AP03334] ROS/Nitric Oxide Detection Defects in this gene areFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.