p47-phox Polyclonal Antibody, 100ul[BT-AP06793] Endonucleases & Exonucleases This gene may be aberrently

This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas

it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer

Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters

Very large introns typically separate the exons encoding the VPS10 domain

Belongs to the resistin/FIZZ family

p47-phox Polyclonal Antibody, 100ul[BT-AP06793] Endonucleases & Exonucleases This gene may be aberrentlyThe protein encoded by NCF1 (neutrophil cytosolic factor 1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.