Akt Polyclonal Antibody, 50ul[BT-AP00337] Micro Centrifuge Tubes A pseudogene of RFC2 has

A pseudogene of RFC2 has been defined on chromosome 2

Mutations in TP63 are associated with ectodermal dysplasia

and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau

frequently with sex reversal

Alternatively spliced transcript variants have been described for this gene

Akt Polyclonal Antibody, 50ul[BT-AP00337] Micro Centrifuge Tubes A pseudogene of RFC2 hasThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a