REN3A Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging Two transcripts of this gene

Two transcripts of this gene are alternatively spliced products

with highest expression in fetal lung

along with GTP

bone marrow and peripheral blood leukocytes

This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein

REN3A Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging Two transcripts of this geneThis gene encodes a protein that is part of a post splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense mediated mRNA decay (NMD). When translation ends upstream from the last exon exon junction this triggers NMD to degrade mRNAs containing