PARK2 Polyclonal Antibody, 50ul Rotator Mutations in GP1BA

Mutations in GP1BA

This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I)

This gene encodes a male meiotic metaphase chromosome-associated acidic protein

It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins

The RAD54 homolog B encoded by RAD54B belongs to the DEAD-like helicase superfamily

PARK2 Polyclonal Antibody, 50ul Rotator Mutations in GP1BAThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this