HES3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The nuclear RNA export factor

The nuclear RNA export factor 1 of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA

Pseudogenes of this gene are known to exist on chromosomes two and nine

a DNA-activated protein kinase involved in the repair of DNA double-strand breaks

It is also involved in cognition

Proteins of this subfamily| also referred to as alpha-CPs| bind to RNA with a specificity for C-rich pyrimidine regions

HES3 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos The nuclear RNA export factorHas a particular type of basic domain (presence of a helix interrupting proline) that binds to the N box (CACNAG), rather than the canonical E box (CANNTG).,The C terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy related proteins.,Transcriptional repressor of genes that require a bHLH protein for their