BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 50ul Serum II and III collagens

II and III collagens

This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment

that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA

The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis

both of which serve as precursors in the production of signaling molecules

BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 50ul Serum II and III collagensIntact BH3 motif is required by BIK BID BAK BAD and BAX for their pro apoptotic activity and for their interaction with anti apoptotic members of the Bcl 2 family. The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1 isoform 2 and isoform 4 induce ICE like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl 2. PTM: Phosphorylated upon DNA damage probably by