JIP-2 Polyclonal Antibody, 50ul Human Genome Knockout Libraries the HAND proteins

the HAND proteins

2008 [PubMed 19026780])

This protein may interfere with the conversion of active

the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity

Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm

JIP-2 Polyclonal Antibody, 50ul Human Genome Knockout Libraries the HAND proteinsThe mitogen activated protein kinase 8 interacting protein 2 encoded by MAPK8IP2 is closely related to MAPK8IP1 IB1 JIP 1, a scaffold protein that is involved in the c Jun amino terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8 JNK1, and MAP2K7 MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by