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Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) and to a lesser extent

SKU: 8403127047

4.5
EUR123.75 EUR170.75

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Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) and to a lesser extentThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

and to a lesser extent

Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane

These proteins have been implicated in the development of paraneoplastic disorders resulting from an immune response directed against them

Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood

Elongation of very long chain fatty acids protein 1 (ELOVL1)

Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) and to a lesser extentThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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