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CLCN5 Polyclonal Antibody, 100ul Drying & Desiccation This chemokine is a member

SKU: 83325711076

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CLCN5 Polyclonal Antibody, 100ul Drying & Desiccation This chemokine is a memberThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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Description

This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues

Matrix metallopeptidase 17 is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor

The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol

Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals

and/or allow the binding of lipids to organelles

CLCN5 Polyclonal Antibody, 100ul Drying & Desiccation This chemokine is a memberThis gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

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