mtTFA Polyclonal Antibody, 50ul Pipette Holder Apoptosis antagonizing transcription factor encoded

Apoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12/DLK

as well as with CAP2 and actin

lung and skeletal muscle

An important paralog of this gene is TSHZ1

CSNK1A1 phosphorylates CTNNB1 at Ser-45

mtTFA Polyclonal Antibody, 50ul Pipette Holder Apoptosis antagonizing transcription factor encodedTFAM (transcription factor A, mitochondrial) encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in TFAM are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for TFAM on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.