Raf-1 Polyclonal Antibody, 100ul[BT-AP13537] Recombinant Protein Expression It is part of a

It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p

Mutations in this gene have been linked to exertional myoglobinuria

and also dominant nonimmune chronic idiopathic neutropenia of adults

Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death

DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol

Raf-1 Polyclonal Antibody, 100ul[BT-AP13537] Recombinant Protein Expression It is part of aThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.