Rat Collectrin, TMEM27 ELISA Kit, 96T Serum & Sample Tubes Expression of MEKK4 in mammalian

Expression of MEKK4 in mammalian cells activated the CSBP2 and JNK MAPK pathways

and is associated with increased circulating low-density lipoprotein cholesterol

It may play a role in tumor cell metastasis

The cytogenetic location of this locus has been reported as both 8p11 and 8q11

Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric

Rat Collectrin, TMEM27 ELISA Kit, 96T Serum & Sample Tubes Expression of MEKK4 in mammalianPlays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their activity (By similarity). May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane (By similarity). Regulator of SNARE complex function (PubMed: 16330323). Stimulator of beta cell replication (By similarity).