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Integrin Alpha 4 Polyclonal Antibody, 50ul Sealing Film These read-through transcripts are ubiquitously

SKU: 81344650830

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PLN185.00 PLN212.00

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Integrin Alpha 4 Polyclonal Antibody, 50ul Sealing Film These read-through transcripts are ubiquitouslyITGA4 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell

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Description

These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation

It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site

in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis

Alternatively spliced transcript variants have been described for AKIP1

and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci

Integrin Alpha 4 Polyclonal Antibody, 50ul Sealing Film These read-through transcripts are ubiquitouslyITGA4 encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell

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