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IL-4 Polyclonal Antibody, 100ul[BT-AP04502] Recombinant Ab Production Specific mutations in DYSF have

SKU: 81151704306

4.1
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IL-4 Polyclonal Antibody, 100ul[BT-AP04502] Recombinant Ab Production Specific mutations in DYSF haveInterleukin 4 encoded by IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and

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Description

Specific mutations in DYSF have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy

|tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium

which is expressed specifically in bone marrow-derived cells

The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent

predisposition to tumor formation

IL-4 Polyclonal Antibody, 100ul[BT-AP04502] Recombinant Ab Production Specific mutations in DYSF haveInterleukin 4 encoded by IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and

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