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Ku-70 Polyclonal Antibody, 50ul[BT-AP04892] Custom RNA Oligos This protein and the closely

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Ku-70 Polyclonal Antibody, 50ul[BT-AP04892] Custom RNA Oligos This protein and the closelyThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability

Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome

Specifically

Experience unmatched efficiency with these 15 mL high-performance centrifuge tubes

Alternative splicing results in multiple variants

Ku-70 Polyclonal Antibody, 50ul[BT-AP04892] Custom RNA Oligos This protein and the closelyThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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