SEM4G Rabbit Polyclonal Antibody, 100ul RNA Synthesis Up-regulation of this gene in

Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD

The protein encoded by this gene contains WD-40 domains| in addition to an F-box motif| so it belongs to the Fbw class

yielding ADP and glycerol-3-phosphate

its 150 mL capacity ensures efficient processing

In human retinal pigment epithelial cells the protein localized to centrioles and cilia

SEM4G Rabbit Polyclonal Antibody, 100ul RNA Synthesis Up-regulation of this gene inSemaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins semaphorins and integrins) in the N terminal extracellular portion. Based on sequence and structural similarities semaphorins are put into eight classes: invertebrates contain classes 1 and 2 viruses have class V and vertebrates contain classes 3 7. Semaphorins serve as axon guidance ligands