SGCD Polyclonal Antibody, 20ul Insect Expression May play an important role

May play an important role in lens epithelial to fiber cell terminal differentiation

The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals

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involved in calcium binding and microtubule stabilization

Multiple alternatively spliced transcript variants have been described

SGCD Polyclonal Antibody, 20ul Insect Expression May play an important roleThe protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin glycoprotein complex (DGC). DGC forms a link between the F actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb girdle muscular dystrophy and dilated cardiomyopathy.