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RTN4R Polyclonal Antibody, 50ul Primary Antibodies Mutations in this gene result

SKU: 80243403101

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RTN4R Polyclonal Antibody, 50ul Primary Antibodies Mutations in this gene resultThis gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

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Description

Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions

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and with distal myopathies

The protein is localized to the plasma membrane

7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10

RTN4R Polyclonal Antibody, 50ul Primary Antibodies Mutations in this gene resultThis gene encodes the receptor for reticulon 4, oligodendrocyte myelin glycoprotein and myelin associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

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