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FAT1 Polyclonal Antibody, 100ul Liquid Storage Consumables Tumorigenesis may occur when this

SKU: 80235811831

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FAT1 Polyclonal Antibody, 100ul Liquid Storage Consumables Tumorigenesis may occur when thisThis gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin type repeats. In addition to containing 34 tandem cadherin type repeats, the gene product has five epidermal growth factor (EGF) like repeats and one

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Description

Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles

but only three have been characterized to date

This gene shares sequence similarity with mouse LLRep3

miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines

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FAT1 Polyclonal Antibody, 100ul Liquid Storage Consumables Tumorigenesis may occur when thisThis gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin type repeats. In addition to containing 34 tandem cadherin type repeats, the gene product has five epidermal growth factor (EGF) like repeats and one

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