Paxillin Polyclonal Antibody, 50ul[BT-AP06954] Molecular Biology The ADP ribosylation factor GTPase

The ADP ribosylation factor GTPase activating protein 3 encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins

The protein encoded by this gene belongs to the otogelin family

the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A

PKC also serves as the receptor for phorbol esters| a class of tumor promoters

Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p

Paxillin Polyclonal Antibody, 50ul[BT-AP06954] Molecular Biology The ADP ribosylation factor GTPasePXN (paxillin) encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.