HNF-1Beta Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Mutations in this gene result

Mutations in this gene result in Hartnup disorder

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Two transcript variants resulting from alternative splicing have been identified

PKC subfamily

HNF-1Beta Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Mutations in this gene resultHNF1B encodes a member of the homeodomain containing superfamily of transcription factors. Hepatocyte nuclear factor 1 beta binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1 alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin dependent diabetes