PSMD2 Polyclonal Antibody, 20ul[BT-AP07462] ROS/Nitric Oxide Detection Defects in the cathepsin C

Defects in the cathepsin C have been shown to be a cause of Papillon-Lefevre syndrome

The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus

This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen

The encoded protein does not have a transmembrane domain

A neurturin mutation has been described in a family with Hirschsprung Disease

PSMD2 Polyclonal Antibody, 20ul[BT-AP07462] ROS/Nitric Oxide Detection Defects in the cathepsin CThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non ATPase subunits, and a lid, which contains up to 10 non ATPase subunits.