CD58 Polyclonal Antibody, 100ul[BT-AP02040] Cellular Function Assays In response to TGF-beta signal

In response to TGF-beta signal

It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin

and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD)

There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR)| which results in inflammation of the choroid and retina

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor

CD58 Polyclonal Antibody, 100ul[BT-AP02040] Cellular Function Assays In response to TGF-beta signalThe concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of