GDF-8 Monoclonal Antibody, 50ul Sample Library Tubes alternatively spliced transcript variants encoding

alternatively spliced transcript variants encoding a range of isoforms have been described

Mutations in RAD51C are associated with Fanconi anemia-like syndrome

an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain

S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors

activates other family members during mitosis

GDF-8 Monoclonal Antibody, 50ul Sample Library Tubes alternatively spliced transcript variants encodingThis gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein negatively regulates skeletal muscle cell proliferation