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Rab11-FIP2 Polyclonal Antibody, 50ul ADME Two alternatively spliced transcript variants

SKU: 78300906887

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Rab11-FIP2 Polyclonal Antibody, 50ul ADME Two alternatively spliced transcript variantsA Rab11 effector binding preferentially phosphatidylinositol 3,4,5 trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin coated vesicles. Required in a

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Description

Two alternatively spliced transcript variants encoding distinct proteins have been described

Among its related pathways are Factors involved in megakaryocyte development and platelet production and Platelet activation

This gene and DDX21

where they are degraded by the proteasome

and zebrafish

Rab11-FIP2 Polyclonal Antibody, 50ul ADME Two alternatively spliced transcript variantsA Rab11 effector binding preferentially phosphatidylinositol 3,4,5 trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin coated vesicles. Required in a

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