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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03042] Molecular Biology The SRCR family is defined

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ErbB-3 Polyclonal Antibody, 20ul[BT-AP03042] Molecular Biology The SRCR family is definedERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

The SRCR family is defined by a 100-110 amino acid SRCR domain

The zinc finger protein encoded by ZFPM2 (zinc finger protein

FMN2 (formin 2) is a member of the formin homology protein family

moderately in brain and pituitary gland

but also play a role in other tissues such as bone

ErbB-3 Polyclonal Antibody, 20ul[BT-AP03042] Molecular Biology The SRCR family is definedERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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