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MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 100ul Molecular Biology Alternate splicing results in multiple

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MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 100ul Molecular Biology Alternate splicing results in multiplealternative products: Additional isoforms seem to exist Catalytic activity: Cleaves aggrecan at the 360 Ser Phe 361 site. cofactor: Binds 1 zinc ion per subunit. cofactor: Calcium. disease: May play a role in pathological processes participating in rheumatoid arthritis (RA) associated joint tissue destruction. Autoantigen anti MMP19 are frequent in RA patients. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion

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Description

Alternate splicing results in multiple transcript variants of this gene

May be involved in porphyrin cofactor biosynthesis

plays a role in centriole engagement and microtubule nucleation

The result is a rogue activator protein

but decreased response to IL28B

MMP19 (Cleaved-Tyr98) Rabbit Polyclonal Antibody, 100ul Molecular Biology Alternate splicing results in multiplealternative products: Additional isoforms seem to exist Catalytic activity: Cleaves aggrecan at the 360 Ser Phe 361 site. cofactor: Binds 1 zinc ion per subunit. cofactor: Calcium. disease: May play a role in pathological processes participating in rheumatoid arthritis (RA) associated joint tissue destruction. Autoantigen anti MMP19 are frequent in RA patients. The conserved cysteine present in the cysteine switch motif binds the catalytic zinc ion

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