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CLH1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos It is not currently known

SKU: 77768161854

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CLH1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos It is not currently knownClathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.

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Description

It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome

Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage

however when expressed in cells alone or with other GABAB subunits

|PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8

subunit:Interacts with DDX58 and probably blocks its homomultimerization

CLH1 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos It is not currently knownClathrin is a major protein component of the cytoplasmic face of intracellular organelles, called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains.

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