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Phospho-B23 (T234) Polyclonal Antibody, 20ul Transporters G1/S-phase cyclin E-cdk2

SKU: 77685333304

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Phospho-B23 (T234) Polyclonal Antibody, 20ul Transporters G1/S-phase cyclin E-cdk2NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

G1/S-phase cyclin E-cdk2

MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al

a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage

it contains a conserved lysine residue in the seventh transmembrane domain

Several alternatively spliced transcript variants encoding four distinct isoforms have been reported

Phospho-B23 (T234) Polyclonal Antibody, 20ul Transporters G1/S-phase cyclin E-cdk2NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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