NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library a novel family that links

a novel family that links the chemokine and the transmembrane 4 superfamilies of signaling molecules

TRMT11 (TRNA Methyltransferase 11 Homolog) is a Protein Coding gene

Studies in mice and human suggest that STEAP4 maybe involved in adipocyte development and metabolism

Available sequence data analyses identified splice variants that differ in the 5' UTR

The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease

NPC1 Rabbit Polyclonal Antibody, 100ul Peptide Library a novel family that linksThis gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N terminal domain. It is predicted to have a cytoplasmic C terminus 13 transmembrane domains and 3 large loops in the lumen of the endosome the last loop being at the N terminus. This protein transports low density lipoproteins to late endosomal lysosomal compartments