IFI-16 Polyclonal Antibody, 100ul Shaker&Mixing An important paralog of this

An important paralog of this gene is NAA16

Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres

The encoded protein acts as a transcription factor and may be autoregulatory

This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development

an activating homodimeric C-type lectin-like receptor (CTLR)

IFI-16 Polyclonal Antibody, 100ul Shaker&Mixing An important paralog of thisIFI16 encodes a member of the HIN 200 (hematopoietic interferon inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma 1. It modulates p53 function, and inhibits cell growth in the Ras Raf signaling pathway.