ZnT-8 Polyclonal Antibody, 20ul Immunology Diseases associated with RRAD include

Diseases associated with RRAD include diabetes mellitus

and RUNX3 is frequently deleted or transcriptionally silenced in cancer

which plays a role in cellular survival

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and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade

ZnT-8 Polyclonal Antibody, 20ul Immunology Diseases associated with RRAD includeZinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin secreting INS 1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin dependent