TOK-1 Polyclonal Antibody, 20ul Mammalian Expression and plays a regulatory role

and plays a regulatory role in S phase DNA replication and DNA damage repair

This protein acts as a sequence-specific repressor of transcription

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serves as the scaffold for assembly of the remainder of the transcription complex

and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers

TOK-1 Polyclonal Antibody, 20ul Mammalian Expression and plays a regulatory roleBCCIP (BRCA2 and CDKN1A interacting protein) product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N terminal half shares moderate homology with regions of calmodulin and M calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a