S22AC Rabbit Polyclonal Antibody, 20ul High Speed Micro-Centrifuges The MYC binding protein encoded

The MYC binding protein encoded by MYCBP binds to the N-terminus of the oncogenic protein C-MYC

GBP3 encodes a member of the guanylate-binding protein (GBP) family

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

Mutations in this gene have been associated with thyroid dysgenesis

|PTM:While translation occurs| the particular unfolded structure after the GRR repeat promotes the generation of p50 making it an acceptable substrate for the proteasome

S22AC Rabbit Polyclonal Antibody, 20ul High Speed Micro-Centrifuges The MYC binding protein encodedThe protein encoded by this gene is a member of the organic anion transporter (OAT) family and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate hyperuricemia is associated with increased incidences of gout and mutations in this gene cause renal hypouricemia type 1. Alternative splicing