DMA Polyclonal Antibody, 20ul Immune Repertoire Sequencing this gene is disrupted in

this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion

Reciprocal translocations between chromosomes 17 and 22| where this gene and the gene for platelet-derived growth factor beta are located| are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans| resulting from unregulated expression of the growth factor

and thrombospondin N-terminal-like domains

The encoded isozyme is a soluble cytoplasmic protein

FAS-associated factor 1 encoded by FAF1 binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen

DMA Polyclonal Antibody, 20ul Immune Repertoire Sequencing this gene is disrupted inHLA DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes,