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Histone H2B Polyclonal Antibody, 100ul[BT-AP04030] Filtration At least three alternatively spliced

SKU: 76465846957

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SEK123.75 SEK170.75

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Histone H2B Polyclonal Antibody, 100ul[BT-AP04030] Filtration At least three alternatively splicedHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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Description

At least three alternatively spliced variants encoding distinct proteins have been reported

Mutations in this gene have been associated with Hodgkin lymphoma

PAI-2 and PAI-3 (plasminogen activator inhibitor-1

ITGA2 encodes the alpha subunit of a transmembrane receptor for collagens and related proteins

in humans| loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors

Histone H2B Polyclonal Antibody, 100ul[BT-AP04030] Filtration At least three alternatively splicedHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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