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JMJD2A Monoclonal Antibody, 100ul Recombinant Ab Production It has also been implicated

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JMJD2A Monoclonal Antibody, 100ul Recombinant Ab Production It has also been implicatedThis gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD type zinc fingers. This nuclear protein functions as a trimethylation specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

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It has also been implicated in the pathogenesis of small cell lung cancer

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a type I keratin

cytoplasmic dynein

Fusion of ATF1 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

JMJD2A Monoclonal Antibody, 100ul Recombinant Ab Production It has also been implicatedThis gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD type zinc fingers. This nuclear protein functions as a trimethylation specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

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