eIF4G(Phospho-Ser1108) Rabbit Polyclonal Antibody, 100ul Lysosome Mutations in ZNF592 have been

Mutations in ZNF592 have been associated with autosomal recessive spinocerebellar ataxia

An important paralog of this gene is PLP1

This gene is not highly expressed

Drosophila

Potassium-transporting ATPase alpha chain 2 encoded by ATP12A belongs to the family of P-type cation transport ATPases

eIF4G(Phospho-Ser1108) Rabbit Polyclonal Antibody, 100ul Lysosome Mutations in ZNF592 have beenThe protein encoded by this gene is a component of the multi subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome which is a rate limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP dependent unwinding of 5' terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains