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EGFR(Phospho Thr693) Polyclonal Antibody, 50ul Custom DNA Oligos This putative nuclear transcription factor

SKU: 75148757495

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EGFR(Phospho Thr693) Polyclonal Antibody, 50ul Custom DNA Oligos This putative nuclear transcription factorThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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Description

This putative nuclear transcription factor most likely functions in regulating the response to growth factors

enzyme regulation:Activated by threonine and tyrosine phosphorylation

The binding of this protein to IL3 depends on the beta subunit

Overexpression increases MET activation and promotes invasive growth

Its two SH3 domains direct complex formation with proline-rich regions of other proteins

EGFR(Phospho Thr693) Polyclonal Antibody, 50ul Custom DNA Oligos This putative nuclear transcription factorThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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