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IL-13R Alpha2 Polyclonal Antibody, 50ul[BT-AP04442] ROS/Nitric Oxide Detection Mutations in this gene have

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IL-13R Alpha2 Polyclonal Antibody, 50ul[BT-AP04442] ROS/Nitric Oxide Detection Mutations in this gene haveThe interleukin 13 receptor subunit alpha 2 encoded by IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

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Description

Mutations in this gene have been associated with cylindromatosis| multiple familial trichoepithelioma| and Brooke-Spiegler syndrome

A third variant has been described

With a flat cap and conical bottom

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta

This cytokine is a ligand for interleukin 4 receptor

IL-13R Alpha2 Polyclonal Antibody, 50ul[BT-AP04442] ROS/Nitric Oxide Detection Mutations in this gene haveThe interleukin 13 receptor subunit alpha 2 encoded by IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

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